ELISA Substrates and Reagents
ABclonal Technology Phospho-AKT1-S473 Rabbit pAb
This gene encodes a member of the AKT serine-threonine kinase family, involved in regulating cell proliferation, survival, metabolism, and angiogenesis. AKT proteins are activated by phosphorylation via phosphoinositide 3-kinase (PI3K) and play key roles in various signaling pathways, including those involving receptor tyrosine kinases and G-protein coupled receptors. AKT activation requires phosphorylation of threonine 308 and serine 473. The PI3K/AKT pathway is crucial for tumor cell survival by inhibiting apoptosis and activating survival factors. AKT also interacts with the mTOR pathway, affecting translation initiation and is often dysregulated in cancers. Mutations in this gene are linked to various cancers, Proteus syndrome, Cowden syndrome, and other growth disorders. Multiple transcript variants exist due to alternative splicing.
Crescent Chemical Co Inc TETRAMETHYLBENZIDINE (TMB)
5,5'-Tetramethylbenzidine research grade Substrate for horseradish peroxidase. More sensitive than ABTS and more stable and less toxic than diaminobenzidine. See also TMB Ready-To-Use ELISA Substrate (cat. no. 37068) and SERVAColor TMB Blot Solution (cat. no. 37071). S
Selleck Chemical LLC Coelenterazine 1mg 55779-48-1
Coelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sino Biological Recombinant Human BAFF/BLyS/TNFSF13B Protein (ECD)
A DNA sequence encoding the soluble form of human BAFF (Q9Y275-1) (Ala 134-Leu 285) was expressed and purified.
ABclonal Technology HYAL1 Rabbit mAb
This gene encodes a lysosomal hyaluronidase Hyaluronidases intracellularly degrade hyaluronan one of the major glycosaminoglycans of the extracellular matrix Hyaluronan is thought to be involved in cell proliferation migration and differentiation This enzyme is active at an acidic pH and is the major hyaluronidase in plasma Mutations in this gene are associated with mucopolysaccharidosis type IX or hyaluronidase deficiency The gene is one of several related genes in a region of chromosome 3p21 3 associated with tumor suppression Multiple transcript variants encoding different isoforms have been found for this gene
Sino Biological Recombinant Human BAFF/BLyS/TNFSF13B Protein (Trimer, His & AVI Tag), Avi-tag Biotinylated, MALS-verified
A DNA sequence encoding the Human TNFSF13B (NP_006564.1) (Ala134-Leu285) was expressed with a N-terminal polyhistidine tag followed by an AVI tag.The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed. This construct has a trimer design.
Cayman Chemical p38a MAPK-IN-1 50mg
A p38α MAPK inhibitor (IC50 = 5,500 nM in an HTRF assay); inhibits LPS-induced TNF-α production in THP-1 cells (EC50 = 6,200 nM); has been used in the study of p38α MAPK inhibitor binding interactions and kinetics
Cayman Chemical TStosTRon ELISA ntIsRum 500dtn
An ACSL4 inhibitor (IC50 0.38 UM) selective for ACSL4 over ACSL3 (IC50 >50 UM) and PPARY (IC50 >10 UM)